Wildlife disease is an increasingly important threat to many species of conservation concern. The impact of sarcoptic mange (Sarcoptes scabiei) on wombats is a matter of considerable concern to some members of the wider community, as evidenced by multiple submissions to the recent Senate Inquiry on Australia’s Faunal Extinction Crisis. Sarcoptic mange is an emerging infectious disease, which most likely has been introduced to Australia with European settlers and their domestic animals. It has since spread to native mammals and is considered the most significant disease threat to wild wombats. Sarcoptic mange in wild populations is often debilitating and causes significant morbidity and mortality. This project seeks to establish guidelines on the best practice treatment of Australian wild animals with sarcoptic mange.