Invasive vertebrate species, such as cats and rodents, pose a serious threat to the biodiversity on Tasmanian offshore islands. Many of these islands support threatened species, species found nowhere else, and high concentrations of seabirds. A challenge for managers is determining which islands to focus invasive animal management on, for the purpose of conservation. To help address this, we identified priority islands for cat and rodent management, using a prioritisation model with set budgets under a range of scenarios. We examined 590 islands and 224 of these supported native species of significance.